The ABACus Study consists of two projects: ABACus and ABACus2, which focus on body fatness exposure and the related cancer risk.
The primary focus of the first project: Adulthood BMI trajectories And Cancer using clusters; a pooled analysis of cohorts with repeated BMI measures (ABACus) was to test the role of latent class trajectory modelling to assess life course changes in BMI and the related cancer risk. For more information, please visit the ABACus project page.
The primary focus of the second project: Adolescent and adulthood BMI And Cancer risk using obese-year metrics (ABACus2) is to use the obese-year metric to estimate the cumulative life-course exposure to body fatness and link this with cancer risk and use sophisticated statistical models to identify ‘critical age periods’ to help inform targeted prevention strategies. For more information, please visit the ABACus2 project page.
A related project, the BACARDI study, was conducted in 2019. This project utilised the Salford Integrated Record Database (UK) to investigate the relationship between BMI and 13 cancer types in patients diagnosed with Type 2 Diabetes. For more information, please visit the BARCARDI project page.